{"id":10385,"date":"2026-11-11T21:56:28","date_gmt":"2026-11-11T21:56:28","guid":{"rendered":"https:\/\/silvybrand.com\/?p=10385"},"modified":"2026-11-11T21:56:28","modified_gmt":"2026-11-11T21:56:28","slug":"startup-fights-ai-bioweapons-with-ai","status":"publish","type":"post","link":"https:\/\/silvybrand.com\/?p=10385","title":{"rendered":"A Startup Wants to Fight AI Bioweapons With AI"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<p><span class=\"body lead-in-text\">Frontier AI labs<\/span> have warned that their technology could help <a href=\"https:\/\/www.wired.com\/story\/you-dont-need-ai-to-be-concerned-about-bioweapons-development-but-it-helps\/\" class=\"text link\">develop dangerous bioweapons<\/a>.<\/p>\n<p class=\"paywall\">Now, a startup says it has developed a defense. On Wednesday, Radical Numerics announced that it has developed a new edge model called Omnii Defense that is designed to flag natural and AI-engineered pathogens using a laptop and a USB gene sequencer. It can also run without an internet connection, allowing researchers in the field with spotty connections to use it. Though many scientists say <a href=\"https:\/\/www.wired.com\/story\/why-ai-bioweapons-wont-wipe-out-humanity\/\" class=\"text link\">AI-made bioweapons<\/a> are a low-likelihood threat, Radical Numerics hopes its technology will help researchers and public health officials identify emerging biological threats.<\/p>\n<p class=\"paywall\">Eric Nguyen, cofounder and CEO of Radical Numerics, says he sees a coming arms race in biodefense similar to what\u2019s <a href=\"https:\/\/www.wired.com\/story\/free-chinese-ai-models-are-getting-scary-good-at-hacking\/\" class=\"text link\">playing out in cybersecurity<\/a>, where threat actors and security defenders are <a href=\"https:\/\/www.wired.com\/story\/kernel-panic-the-php-meltdown-shows-how-ai-makes-bugs-more-exploitable\/\" class=\"text link\">leveraging AI<\/a> in an attempt to gain an edge.<\/p>\n<p class=\"paywall\">\u201cWe felt that the biosecurity space was far behind on the defense side,\u201d he says.<\/p>\n<p class=\"paywall\">Nguyen and his cofounders were part of the research team behind Evo and Evo-2, open-source DNA foundation models they worked on during their doctoral research at Stanford University. They founded Radical Numerics in 2025.<\/p>\n<p class=\"paywall\">The San Francisco\u2013based company recently made waves after rolling out Omnii, a new genome language model built on different types of biological information beyond DNA, including RNA, proteins, and epigenetic signals. In October, Radical announced that it used Omnii to <a data-offer-url=\"https:\/\/www.nytimes.com\/2026\/10\/20\/science\/ai-virus-bacteria-radical-numerics.html\" class=\"external-link text link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/www.nytimes.com\/2026\/10\/20\/science\/ai-virus-bacteria-radical-numerics.html&quot;}\" href=\"https:\/\/www.nytimes.com\/2026\/10\/20\/science\/ai-virus-bacteria-radical-numerics.html\" rel=\"nofollow noopener\" target=\"_blank\">create custom bacteriophages<\/a>, viruses that infect and kill specific bacteria, targeting a drug-resistant strain of <em>E. coli.<\/em> Its cocktail was used to treat a sick patient, with special permission from the Food and Drug Administration.<\/p>\n<p class=\"paywall\">Another AI biotech startup, Tabula Bioscience, was also involved in that research, but Radical didn\u2019t disclose the partnership in its <a data-offer-url=\"https:\/\/www.radicalnumerics.ai\/blog\/omnii-phage\" class=\"external-link text link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/www.radicalnumerics.ai\/blog\/omnii-phage&quot;}\" href=\"https:\/\/www.radicalnumerics.ai\/blog\/omnii-phage\" rel=\"nofollow noopener\" target=\"_blank\">announcement<\/a> last month. The omission led Harvard geneticist George Church, who was an adviser to both companies, to <a data-offer-url=\"https:\/\/www.nytimes.com\/2026\/11\/06\/science\/radical-numerics-tabula-phage.html\" class=\"external-link text link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/www.nytimes.com\/2026\/11\/06\/science\/radical-numerics-tabula-phage.html&quot;}\" href=\"https:\/\/www.nytimes.com\/2026\/11\/06\/science\/radical-numerics-tabula-phage.html\" rel=\"nofollow noopener\" target=\"_blank\">resign from his role<\/a> at Radical last week.<\/p>\n<p class=\"paywall\">Omnii Defense, the company\u2019s latest tool, makes multiple predictions about a sequence, including the odds of it being pathogenic or AI-generated and what taxonomic group it most closely resembles. The model assigns a genome a \u201cthreat score\u201d between zero and one that combines the likelihood of unnaturalness with functional predictions. The higher the score, the higher the threat.<\/p>\n<p class=\"paywall\">Earlier biodefense tools, such as the federally funded Finding Engineering-Linked Indicators, or Felix, can compare genetic sequences of interest against libraries of known organisms, essentially searching for cataloged matches. That can be helpful in a scenario where a bad actor has made a few tweaks to an existing pathogen. But they aren\u2019t designed to make predictions in the way that Omnii is.<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.wired.com\/story\/startup-fights-ai-bioweapons-with-ai\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Frontier AI labs have warned that their technology could help develop dangerous bioweapons. Now, a startup says it has developed a defense. On Wednesday, Radical Numerics announced that it has developed a new edge model called Omnii Defense that is designed to flag natural and AI-engineered pathogens using a laptop and a USB gene sequencer. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10386,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[31,83,304,780,1283],"class_list":["post-10385","post","type-post","status-publish","format-standard","has-post-thumbnail","category-gadgets","tag-ai","tag-artificial-intelligence","tag-biology","tag-biotech","tag-weapons"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A Startup Wants to Fight AI Bioweapons With AI - Silvybrand Lifestyle Blog<\/title>\n<meta name=\"description\" content=\"Radical Numerics has developed a model that it says can identify natural and AI-engineered pathogens without an internet connection.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/silvybrand.com\/?p=10385\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Startup Wants to Fight AI Bioweapons With AI - 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