{"id":2597,"date":"2026-06-24T05:58:01","date_gmt":"2026-06-24T05:58:01","guid":{"rendered":"https:\/\/silvybrand.com\/?p=2597"},"modified":"2026-06-24T05:58:01","modified_gmt":"2026-06-24T05:58:01","slug":"startup-using-polymers-and-blue-light-to-help-tissue-heal","status":"publish","type":"post","link":"https:\/\/silvybrand.com\/?p=2597","title":{"rendered":"French Startup Uses Special Polymers to Better Help Nerves Heal"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<p><span class=\"lead-in-text-callout\">Roughly 500,000 Americans<\/span> suffer <a href=\"https:\/\/www.wired.com\/video\/watch\/tech-support-neurologist-answers-nerve-questions-from-twitter\" class=\"text link\">nerve injuries<\/a> that require treatment each year, whether from an errant attempt to hack out an avocado pit or an unfortunate woodworking accident. Many will never get full feeling back in their fingers. But a startup has developed a thick and sticky liquid that could change that, and it&#8217;s begun deploying it with surgeons in the US.<\/p>\n<p class=\"paywall\">French firm Tissium is working to replace and supplement medical stitches with a liquid that attaches to tissue when exposed to light. A biopolymer made of fatty acid and glycerol\u2014both of which naturally occur in the body\u2014the liquid acts like a splint to hold the nerves in place while the tissue mends itself. It then biodegrades after the body heals, leaving nerves intact.<\/p>\n<p class=\"paywall\">Peripheral nerves make up the sprawling network of the nervous system, branching off from the brain and the spinal cord to the rest of the body. When one is cut, often through injuries involving knives or machinery, the two ends need to be held in place while the nerve slowly repairs itself. Fail to do so, and you\u2019ll be left with symptoms ranging from tingling and no feeling at all to electrical-like stabbing pain.<\/p>\n<p class=\"paywall\">Aligning severed nerves requires micro-sutures, which is \u201ca very delicate technique,\u201d Tissium cofounder and deputy chief executive officer Maria Pereira says, \u201cso we are trying to provide a new way and a better way for peripheral nerves to be prepared in a consistent manner, a less traumatic matter, and with better patient outcomes.\u201d<\/p>\n<p class=\"paywall\">The company ran a trial with 12 patients in the US who had injured nerves in their fingers. All 12 regained the ability to feel temperature, pain, texture, and light touch in their fingers\u2014compared to a <a data-offer-url=\"https:\/\/innosurge.com\/sites\/default\/files\/uploads\/product-documents\/Outcomes%20of%20short-gap%20sensory%20nerve%20injuries%20reconsructed%20with%20processed%20nerve%20allografts.pdf\" class=\"external-link text link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/innosurge.com\/sites\/default\/files\/uploads\/product-documents\/Outcomes%20of%20short-gap%20sensory%20nerve%20injuries%20reconsructed%20with%20processed%20nerve%20allografts.pdf&quot;}\" href=\"https:\/\/innosurge.com\/sites\/default\/files\/uploads\/product-documents\/Outcomes%20of%20short-gap%20sensory%20nerve%20injuries%20reconsructed%20with%20processed%20nerve%20allografts.pdf\" rel=\"nofollow noopener\" target=\"_blank\">little over 80 percent<\/a> with other techniques. None reported pain or device-related complications a year later. The treatment is already available for surgeons to purchase in the US.<\/p>\n<p class=\"paywall\">\u201cWhile further evidence is needed, it\u2019s exciting to see more advanced biomaterials and regenerative medical techniques at the disposal of the modern surgeon,\u201d says Simran Chana, a surgeon, materials scientist, and director of the Frontier Technologies Laboratory at the University of Cambridge. (Chana isn\u2019t involved with Tissium\u2019s work.)<\/p>\n<p class=\"paywall\">Tissium has raised \u20ac30 million in private investments from venture capital firms and family offices to expand commercialization, the firm tells WIRED exclusively, plus \u20ac30 million in debt financing from the European Union\u2019s lending arm, the European Investment Bank. The firm will continue to manufacture its product, which received FDA marketing approval last year, in northern France.<\/p>\n<p class=\"paywall\">The funds will also support the development of applying the technology to other issues: Tissium expects to enroll around 200 patients in a US trial to help the body heal after hernia treatment. Surgeons heal hernias by pushing the bulging organ or tissue back through the muscle wall and then reinforcing the area with stitches and mesh. Currently, \u201cthere can be some inconsistency on how the sutures are performed, which can impact outcomes,\u201d says Pereira, who is also the company\u2019s chief innovation officer. She adds that Tissium\u2019s treatment can provide that consistency, which can in turn improve the recovery process.<\/p>\n<p class=\"paywall\">While she is finalizing the results of a European study testing the treatment on 78 patients undergoing hernia repair, Pereira says that surgeons have been able to apply Tissium\u2019s goo 100 percent of the time and that patients show signs of improved quality of life in terms of pain levels, recovery, and activities, and a lower recurrence rate of hernias.<\/p>\n<p class=\"paywall\">Tissium is also developing products for cardiovascular reconstruction, which was the initial application Pereira conceived of while earning a PhD in bioengineering nearly 20 years ago. The company is preparing to launch a randomized pivotal trial in the US for its cardiovascular product, which the new funding will support.<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.wired.com\/story\/startup-using-polymers-and-blue-light-to-help-tissue-heal\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Roughly 500,000 Americans suffer nerve injuries that require treatment each year, whether from an errant attempt to hack out an avocado pit or an unfortunate woodworking accident. Many will never get full feeling back in their fingers. But a startup has developed a thick and sticky liquid that could change that, and it&#8217;s begun deploying [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2598,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[780,141,358,808,354],"class_list":["post-2597","post","type-post","status-publish","format-standard","has-post-thumbnail","category-gadgets","tag-biotech","tag-health","tag-medicine","tag-rampd-and-inventions","tag-startups"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>French Startup Uses Special Polymers to Better Help Nerves Heal - Silvybrand Lifestyle Blog<\/title>\n<meta name=\"description\" content=\"The biodegradable material can help improve healing after surgery\u2014or an avocado-related accident.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/silvybrand.com\/?p=2597\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"French Startup Uses Special Polymers to Better Help Nerves Heal - 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